乳香中三萜类化合物和药理活性的研究进展

摘要

In this study, the recent progress in the research of triterpenoids and pharmacological activities of frankincense, the gum resin of Boswellia carterii or the other plants to the same species mainly consisting of chemical constituents, such as pentacyclic triterpenoid and tetracyclic triterpenoid, was reviewed. Investigations demonstrated that resin had the following pharmacological effects: anti-inflammatory, antitumor, inducing differentiation and apoptosis, anti-ulcer, hypoglycemic action, improvement on learning and memory, etc. The results also indicated that fewer adverse reactions and potential medicinal value of this material. The research will provide reference for further research of Boswellia carterii.%乳香为橄榄科植物乳香树或同属植物的胶状树脂，主要活性成分为五环三萜、四环三萜等三萜类化合物。现代药理研究表明乳香有抗炎、抗肿瘤、诱导分化凋亡、抗溃疡、降糖、改善学习记忆等药理活性，在抗炎、抗肿瘤方面药理研究较为深入，不良反应少，有潜在的药用价值。通过查阅文献，对近五年来乳香三萜类成分及其药理作用研究进展进行综述，为乳香的进一步研究提供参考。