急性冠脉综合征患者焦虑抑郁情绪的随访

摘要

目的 观察急性冠脉综合征(acute coronary syndrome,ACS)患者焦虑抑郁情绪的变化.方法 对782例ACS患者的焦虑抑郁情绪进行平均(8.0±5.8)m的随访测评,应用综合性医院情绪测量表(hospital anxiety and depression scales,HADS)、贝克焦虑量表(Beck Anxiety Inventory,BAI)和贝克抑郁量表(Beck Depression Inventory,BDI),分析ACS患者焦虑抑郁情绪的变化.结果 与基线期相比,ACS患者的抑郁评分下降具有统计学意义[(7.07±5.37) vs(6.28±5.51),P＜0.05],焦虑评分下降无统计学意义(P＞0.05),焦虑、抑郁的构成比例无统计学意义(P＞0.05).结论 ACS后抑郁程度虽然呈现自然下降趋势,但构成比例降低却无统计学意义,故仍需早发现,早治愈.关于ACS后的焦虑有待进一步深入研究.%Objective To observe changes in anxiety and depression symptoms in acute coronary syndrome patients. Methods A prospective cohort study of 782 patients with ACS were followed up anxiety and depression symptoms were assessed and collected, application of hospital anxiety and depression scales (HADS)、beck anxiety inventory (BAI) and beck depression inventory (BDI). Results The follow-up Beck depression inventory (BDI) score decreased significantly compared with the baseline BDI score [(7.07±5.37) vs (6.28±5.51, P<0.05]. Meanwhile scores of anxiety symptoms and proportion of anxiety and depression were found no any significant changes (P > 0.05). Conclusion Among ACS population, though the depression level was decline spontaneously 7 months later, the proportions of anxiety and depression were still as high as the baseline, So as for the improvement of clinic outcome of ACS population, post-ACS depression should be assessed and treated effectively as early as possible. In the case of post-ACS anxiety, large sample and long term investigations were needed to make it clear.