经颈静脉肝内门体分流术治疗肝硬化顽固性腹水8例

摘要

Objective To observe the effects of the treatment of refractory ascites in cirrhotic patients using transjugular intrahepatic portosystemic shunt (TIPS). Methods The clinical effects of eight cirrhotic patients with refractory ascites who were treated by TIPS were observed. Then we conducted the follow-up and measured the liver function, renal function, blood routine, blood ammonia and complications of the patients. Results The portal venous pressure declined significantly after TIPS. The abdominal girth reduced significantly than before. The urine volume increased significantly than before. Three cases were markedly effective. Four cases were effective.One patient died because of chronic liver failure. Conclusion The effects of the treatment of refractory ascites in cirrhotic patients using TIPS are exact.%目的 观察采用经颈静脉肝内门体分流术(transjugular intrahepatic portosystemic shunt, TIPS) 治疗肝硬化顽固性腹水患者的疗效.方法 对8例肝硬化顽固性腹水患者采用TIPS治疗, 观察其临床疗效, 并对肝功能、血氨、凝血酶原时间及并发症等指标进行随访观察.结果 对于肝硬化顽固性腹水的患者行TIPS治疗后门静脉压力显著下降, 患者腹围显著小于治疗前, 尿量显著增加.显效3例, 有效4例.1例患者因穿刺后肝包膜出血, 予行肝动脉栓塞后导致慢性肝功能衰竭而死亡.结论 TIPS治疗肝硬化顽固性腹水疗效确切.