广州地区高胆固醇血症与膳食危险因素的病例对照研究

摘要

目的：探讨广州地区膳食因素在高胆固醇血症发病中的作用。方法：以1：1病例对照研究方法，于广州南方医院体检中心筛选高胆固醇血症患者200人为病例组，并选取同时期来该院体检的与相应病例年龄、性别、民族、学历配对的健康人群为对照组。结果：单因素分析显示，每日食用叶类蔬菜（OR=0．5，95％cI0．3，0．8）及豆类制品（OR=0．4，95％c10．2，0．9）可降低高胆固醇血症的发生。在调整体质指数的基础上，多因素Logistic回归分析表明，食用叶类蔬菜1-3次／d（OR=0．5，95％cI0．3，0．8）及每日食用豆类制品（OP=0．4，95％C10．2，0．9）为高胆固醇血症的保护因素。其余食物种类及饮料的摄入频率在两组间无显著差异。结论：叶类蔬菜、豆类及豆制品为高胆固醇血症的保护因素。%[Objective] To explore the association between hypercholesterolemia and dietary patterns. [Method] We recruited 200 subjects who were first diagnosed as hypercholesterolemia in Nanfang hospital and matched them （age, gender, ethnic, education） with 200 participants without hyperlipemia with 1：1 matched case - control study. [Result] Consumption of leafy vegetables 1-3 times per day and daily consumption of soybean products could significantly protect the subjects against hypercholesterolemia in single factor analysis, while after controlling body mass index, this protective effects still existed. Other food items and beverages were not associated with hypercholesterolemia. [Conclusion] Leafy vegetables and soybean products had protective effects against hypercholesterolemia in Guangzhou population.