量化运动处方对肥胖2型糖尿病患者代谢指标的影响

摘要

目的：探讨量化运动处方对肥胖2型糖尿病患者代谢指标的影响。方法根据体重指数(BMI)将2型糖尿病患者分为正常体重组及肥胖组，均实施6个月的量化运动处方，分别观察3个月及6个月的体重指数(BMI)、空腹血糖(FBG)、餐后2h血糖、糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)及空腹胰岛素水平。结果1.3个月后，肥胖组的BMI(下降值为2.4kg/m2)、餐后2h血糖(下降值为1.6mmol/L)、TG(下降值为0.6mmol/L)及空腹胰岛素(下降值为2.2mU/L)的下降幅度均明显高于正常体重组(P<0.05)。2.6个月后，肥胖组的BMI(下降值为4.6kg/m2)、FBG(下降值为2.7mmol/L)、餐后2h血糖(下降值为3.5mmol/L)、HbA1c(下降值为1.2%)、TG(下降值为0.9mmol/L)、空腹胰岛素(下降值为3.4mU/L)的下降均明显高于体重正常组(P<0.05)。结论肥胖的2型糖尿病患者能从运动处方带来更多代谢指标更大程度的改善，并且随着时间的延长，效果更明显。%Objective To investigate the impacts of quantitative exercise prescription on metabolicindices of obese patients with type 2 diabetes mellitus. Methods All of the diabetes subjects were divided into two subunits as normal weight group and obesity weight group by the body mass index (BMI). Then all the subjects executed the quantitative exercise prescriptions for 6 months. The fasting blood glucose(FBG), postprandial blood glucose, hemoglobin A1C(HbA1c), triglyceride(TG), total cholesterol(TC) and fasting insulin were observed in the third month and the sixth month time points. Results 1. After 3 months, the decrease of BMI(2.4kg/m2), postprandial glucose(1.6mmol/L), TG(0.6mmol/L) and fasting insulin(2.2mu/L) in obesity weight group were signifi-cantly higher than that in the normal weight group(P<0.05). 2. After 6 months, the decrease of BMI(4.6kg/m2), FBG(2.7mmol/L) , postprandial glucose(3.5mmol/L), HbA1c(1.2%), TG(0.9mmol/L) and fasting insulin (3.4mU/L) in obesity weight group were signifi-cantly higher than that in the normal weight group (P<0.05). Conclusion The obese patients with type 2 diabetes mellitus could get better treatment from the quantitative exercise prescriptions than the normal weight patients with type 2 diabetes mellitus, and as the extension of time, the treatment advantage will be more obvious.