郴州市第一人民医院350例药品不良反应报告分析

摘要

OBJECTIVE:To investigate the characteristics and regularity of the adverse drug reactions ( ADRs) in Chenzhou First People's Hospital so as to promote clinical rational use of drugs.METHODS: 350 ADR reports collected from that hospital in 2013 were analyzed statistically in respects of patients'age, sex, routes of administration, clinical manifestation and types of causative drugs etc.RESULTS: Of the 350 ADR cases, ADR was more often seen in the patients aged 40-60 years, with female showing higher proportion than males; intravenous administration was the main route of administration, accounting for 54.86%; lesions of skin and its appendants were the main clinical manifestations, occupying 33.43%; a total of 172 categories of drugs were involved, among which antibiotics took the lead (31.14%) .CONCLUSIONS:Great importance should be attached to monitoring of ADR and medication so as to improve the level of rational use of drugs.%目的：了解郴州市第一人民医院药品不良反应（ ADR）发生的特点及规律，促进临床合理用药。方法：收集该院2013年上报的350例ADR报告，按患者年龄、性别、给药途径、临床表现、所涉及的药品等进行统计分析。结果：350例ADR报告中，患者以40～60岁为主，女性较男性多；给药途径以静脉注射（占54．86％）居多；临床表现以皮肤及其附件损害最常见，占33．43％；ADR涉及药品172种，其中抗感染药引发的ADR最多，占31．14％。结论：临床应重视ADR的监测工作，加强对患者用药过程的观察，提高合理用药水平。