目的:探讨糖肾康微丸薄膜包衣工艺的最佳工艺.方法:考察包衣辅料和包衣增质量对糖肾康微丸的影响,考察包衣工艺参数(风机频率、雾化压力、包衣液流速和物料温度)对包衣效果的影响.结果:最佳包衣工艺为,采用上海卡乐康包衣技术有限公司生产的欧巴代薄膜包衣粉,包衣增质量3％,进出风频率均为1500 r/min,雾化压力为0.3 MPa,包衣液流速为2～4 r/min,物料温度为45℃.结论:本工艺操作简单、稳定可行.%OBJECTIVE: To probe into the optimized thin-film coating process for Tangshenkang pellets . METHODS: The effects of coating materials and coating conditions on the coating process were investigated by centrifugal coating method .And effects of coating process parameters ( fan frequency , atomization pressure , rate of coating fluid flow and material temperature ) on coating process were observed .RESULTS: The best coating process were as follows: the thin-film coating powder of Opadry ? from Shanghai Colorcon Coating Technology Co .LTD was adopted, the coating weight gain was 3％, the inlet and outlet wind frequencies were 1500 rotations per minute , the atomization pressure was 0.3 MPa, the rate of coating liquid flow was 2-4 rotations per minute , and the material temperature was 45 ℃.CONCLUSIONS:The process is simple , stable and feasible .
展开▼
