We investigated the deformation behavior of a new biomedical Cu-bearing titanium alloy(Ti-645(Ti-6.06 A1-3.75 V-4.85 Cu, in wt%)) to optimize its microstructure control and the hot-working process. The results showed that true stress-true strain curve of Ti-645 alloy was susceptible to both deformation temperature and strain rate. The microstructure of Ti-645 alloy was significantly changed from equiaxed grain to acicular one with the deformation temperature while a notable decrease in grain size was recorded as well. Dynamic recovery(DRV) and dynamic recrystallization(DRX) obviously existed during the thermal compression of Ti-645 alloy. The apparent activation energies in(α+β) phase and β single phase regions were calculated to be 495.21 kJ mol^(-1) and 195.69 kJ mol^(-1), respectively. The processing map showed that the alloy had a large hot-working region whereas the optimum window occurred in the strain rate range of 0.001-0.1 s^(-1), and temperature range of 900-960℃ and 1000-1050℃. The obtained results could provide a technological basis for the design of hot working procedure of Ti-645 alloy to optimize the material design and widen the potential application of Ti-645 alloy in clinic.
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