超声监测怡开治疗甲状腺相关眼病的价值

摘要

目的 研究利用彩色多普勒超声监测怡开治疗甲状腺相关眼病(TAO)的价值.方法 把94例病人分为二组,第一组34例,作怡开治疗组.第二组60例作对照组.第一组在进行常规治疗基础上加服怡开480u2日三次,连续三个月,利用彩色多普勒超声诊断仪对每个患者每月检查双眼轴距、内外直肌厚度、视网膜中央动脉收缩期峰值流速.结果 怡开治疗组与对照组比较眼球轴距、内外直肌厚度、视网膜中央动脉收缩期峰值流速,均有显著统计学差异,尤以内外直肌厚度效果显著.结论 彩色多普勒超声检查是一种最直观地观察眼球轴距、内外直肌厚度、及眼部血供的检查方法 ,在TAO诊断和治疗过程中,它可作为一种常规检查和监测方法 ,同时怡开本身不失为一种治疗TAO的辅助药物.%Objective Study the value of pancreatic kininogenase on TAO by color dopple ultrasound. Methods There are 94 cases divided into two groups.One is treatment group with 34 cases given pancreatic kininogenase. The other is control group. The treatment group had been continuously given 480unit pancreatic kininogenase three times perday for three months based on routine therapy. Then the binocular axle base, the thickness of medial and external rectus, the peak systolic velocities of central retinal artery were measured by color dopple ultrasound monthly.Result Carnpare with the control group, the trreatment group has significant statistical difference in the binocular axle base, the thickness of inner and external rectus, and the peak systolic velocities of central retinal artery, especially in the thickness of inner and external rectus. Conclusion Color dopple ultronography is the most direct method to observe the binocular axle base, thr thickness of inner and external rectus and blood supply of the eye ball. It can be used as rotine examination method and monitoring method in course of treatment of TAO. Meanwhile pancreatic kininogenase is an adjuvant drug for TAO.