Objective To explore the Clinical features and rational treatments and early precautins of late vitamine K(Vitk) deficiency symptom in infant. Methods The Clinical data of 25 patients diagnosed as late Vitk deficiency symptom were analyzed. Results 23 cases(92%)came from rural, 24 cases(96%) was breast-feeding, 1 case was mixed feeding. erroneous diagnosis14 cases(56%), anemia24 cases(96%), intracranial hemorrhage 17 cases(68%). All patients were treated by Vitk, part patients were donated blood,12 cases(48%)recovered completely,7 cases had significant improvement,4 cases were discharged from the hospital with no improvement and 2 case(8%) died.10 cases were fellowed up, 5cases occurred residual. Conclusion Late Vitk deficiency symptom usually occurs in little infant come from rural feeded with breast feeding. Incidence, erroneous diagnosis rate, mortality and residual rate of intracranial hemorrhage are high. Early diagnosis, timely rational treatments and early precautions are important.% 目的探讨婴儿晚发性维生素(Vit)K缺乏症临床特点、合理治疗及早期预防。方法对25例晚发性VitK缺乏症患儿的临床资料进行分析。结果25例患者,来自农村23例(92%)；母乳喂养24例(96%),混合喂养1例；误诊14例(56%)；发生贫血24例(96%),颅内出血17例(68%)；经过VitK及输血等治疗,治愈12例(48%),好转7例(28%),自动出院4例(16%),死亡2例(8%)；随访10例,5例有后遗症。结论农村单纯母乳喂养小婴儿易患此病,颅内出血发生率、误诊率、病死率及后遗症发生率较高,早期诊断、及时合理治疗及早期预防至关重要。
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