新生儿血小板减少症51例临床分析

摘要

Objective To investigate the common pathogeny and treatment of neonatal thrombocytopenia. Methods Retrospective analysis about clinical datas of 51 cases of neonatal thrombocytopenia admitted in our hospital Neonatology from January 2009 to December 2011. Results In the pathogeny, 22 cases neonatal infections(43.14%), 11 cases asphyxia at birth(21.57%), 11 cases pathological jaundice(21.57%), 3 cases respiratory distress syndrome(5.88%), 2 cases neonatal scleredema(3.92%), 2 cases multiple organ dysfunction syndrome(3.92%). The rate of cure and improvement was 86.27%, 2 cases death. Conclution Infections and asphyxia are major causes of neonatal thrombocytopenia, so primary disease treatment is critical, complemented by short-term hormone and intravenous gamma globulin, good efficacy, most good prognosis.%　　目的探讨新生儿血小板减少症的常见病因及治疗原则.方法回顾性分析新生儿科2009年1月~2011年12月收治的51例新生儿血小板减少症患儿的临床资料.结果病因中新生儿感染22例(43.14%)，出生时窒息11例(21.57%)，病理性黄疸11例(占21.57%)，呼吸窘迫综合征(RDS)3例(5.88%)；新生儿硬肿症2例(占3.92%)；多脏器功能衰竭(MODS)2例(占3.92%).治愈好转率达86.27%，死亡2例.结论感染、窒息是新生儿血小板减少症的主要病因，针对原发病治疗是关键，辅以短期激素及静脉注射丙种球蛋白，疗效确切，大多预后良好.