血浆D-二聚体定量检测在诊断和治疗监测肺静脉栓塞中的临床价值

摘要

Objective To investigate the quantitative detection of plasma D-dimer testing in the diagnosis and treatment of pulmonary vein thrombosis in clinical value. Method The experimental group was pulmonary vein thrombosis in patients with 100 in the control group of 30 healthy people.Respectively,two groups of quantitative D-dimer testing. Results Using latex particle enhanced turbidimetric method to detect the two dimer, results are as follows:The experimental group (2750 ± 1245)μg/L,the control group (205 ± 86)μg/mg(P<0.01). Conclusion Pulmonary vein thrombosis disease patients showed ifbrinolytic, plasma D-dimer levels have more serious increased, signiifcantly higher. D-dimer levels with proven pulmonary vein thrombosis are closely linked. Latex particle enhanced turbidimetric method is automated, sensitive, rapid characteristics, is conducive to pulmonary vein thrombosis detection and screening. For disease diagnosis and detection with tracking guidance.%目的：探讨血浆D-二聚体定量检测在诊断和治疗监测肺静脉栓塞中的临床应用价值。方法选取了2011年5月～2012年12月佛山市南海区第七人民医院收治的肺静脉栓塞患者100例为实验组，对照组为30例健康人群。分别对两组人员的血浆D-二聚体进行定量检测。结果使用乳胶微粒增强免疫比浊法对两组D-二聚体含量进行检测，实验组（2750±1245）µg/L，对照组（205±86）µg/mg，差异有统计学意义（P＜0.01)。结论肺静脉栓塞疾病患者表现出继发性纤溶亢进，血浆D-二聚体的含量有比较严重的增高，明显高于对照组。证明D-二聚体的含量与肺静脉栓塞有紧密的联系，全自动乳胶微粒增强免疫比浊法检测具有自动化、敏感、快速的特点，有利于肺静脉栓塞的检测和筛选，对疾病诊断和治疗监测具有追踪指导意义。