纳洛酮联合醒脑静治疗急性重度酒精中毒49例

摘要

Objective To investigate the clinical efficacy of naloxone combined with Xingnaojing injection in the treatment of acute severe alcoholism. Methods 98 cases of acute alcohol poisoning were randomly divided into control group and observation group. Control group were treated with conventional therapy plus naloxone. The observation group:on the basis of routine treatment, naloxone combined with Xingnaojing treatment. To observe the consciousness recovery time, when there is no headache and dizziness, nausea and vomiting, palpitations, chest tightness, fatigue and decreased blood pressure and other symptoms of patients in two groups. Results The patients in observation group consciousness recovery time was (3.3 ± 0.9) h was significantly less than that of the control group (3.8 ± 1) h, the difference was statistically significant (P<0.05). Headache, dizziness, nausea and vomiting, palpitations, chest tightness, blood pressure and reduce the incidence of complications of the observation group was significantly lower than that of the control group, the difference was significant (P<0.05). Conclusion Naloxone combined with Xingnaojing injection in the treatment of patients with acute severe alcoholism, can effectively reduce the incidence of consciousness recovery time and clinical complications.%目的：探讨纳洛酮联合醒脑静治疗急性重度酒精中毒的临床疗效。方法98例急性重度酒精中毒患者，随机分成对照组和观察组，各49例。对照组给予常规治疗加用纳洛酮，观察组在常规治疗的基础上给予纳洛酮联合醒脑静治疗。观察两组患者意识恢复时间，酒醒后有无头痛头晕、恶心呕吐、心悸胸闷、全身乏力和血压降低等不适症状。结果观察组患者意识恢复时间为(3.3±0.9)h明显少于对照组(3.8±1.0)h，差异具有统计学意义(P<0.05)。观察组头痛头晕、恶心呕吐、心悸胸闷、血压降低并发症发生率明显低于对照组，差异由统计学意义(P<0.05)。结论纳洛酮联合醒脑静治疗急性重度酒精中毒患者能有效减少患者意识恢复时间和临床并发症的发生。