运动疗法对2型糖尿病干预效果的Meta分析

摘要

Objective To evaluate the effectiveness and safety of physical therapy for the treatment of type 2 diabetes mel litus by Meta-analysis. Methods The inclusion and exclusion criteria were developed by searching CMCC, CNKI and WANFANG database. And the fasting plasma glucose and glycated hemoglobin were selected as the evaluation index. A Meta-analysis was per formed by Rev-Man 4.0 software. Results A total of 16 source documents (1152 patients with diabetes mellitus involved) matched inclusion criteria. After Meta-analysis of results, there was significant difference in fasting plasma glucose and glycosylated hemoglo bin between exercise therapy group and control group (P <0.01). Conclusion The effectiveness for the treatment of type 2 diabe tes mellitus may improve when combined with exercise therapy. However, these results need confirmation through random and rigor ously controlled trials.%目的 通过Meta分析评价运动疗法辅助治疗2型糖尿病的效果和安全性.方法 查找中国期刊全文数据库、中国科技期刊全文数据库、万方数据库相关文献,制定纳入和排除标准,并选择空腹血糖及糖化血红蛋白作为评价指标,利用Rev-Man 4软件进行Meta分析.结果 共有16篇文献1152例糖尿病入选.对结果进行Meta分析后发现,运动治疗组和对照组空腹血糖及糖化血红蛋白比较差异均有统计学意义(P＜0.01).结论 运动疗法辅助治疗2型糖尿病有一定的效果,但仍需要多中心、大样本随机对照试验进一步验证.