目的：探讨胃神经内分泌癌(neuroendocrine neoplasm,NEN)及胃未分化癌的临床特点,以减少误诊、误治。方法对误诊为胃恶性淋巴瘤的胃 NEN 及胃未分化癌各1例的临床资料进行回顾性分析。结果本组例1因腹痛、腹胀1个月,加重伴排柏油样便、乏力半个月就诊；例2因腹痛、腹胀2个月就诊。2例胃镜及活检均考虑胃恶性淋巴瘤,术前对症治疗后症状未改善,因患者有消化道出血及贫血,遂转外科手术治疗。术后病理检查分别确诊为胃 NEN 及胃未分化癌。结论胃 NEN 及未分化癌症状、体征不典型,易误诊、误治,胃镜活检多点、足量、足够深度取材可提高检出率。%Objective To study the clinical manifestations and pathological features of neuroendocrine gastric carci-noma and gastric anaplastic carcinoma and reduce rates of misdiagnosis and mistreatment. Methods Retrospective analysis of the clinical data of neuroendocrine gastric carcinoma and gastric anaplastic carcinoma misdiagnosed as gastric malignant lym-phoma was carried out. Results In this report, the patient of case one was admitted for abdominal discomfort with black stool and weakness and the patient of case two was admitted for abdominal discomfort for two months. Gastric malignant lymphoma was suspected following gastroscopic and pathological detection of the two cases. The patients did not turn for better after treat-ment in department of hematology. The patients had gastrointestinal bleeding and anemia, then the patients underwent surgical treatment. Postoperative pathology confirmed neuroendocrine gastric carcinoma and gastric anaplastic carcinoma. Conclusion The clinical manifestations of neuroendocrine gastric carcinoma and gastric anaplastic carcinoma lack specificity and may easily be misdiagnosed as gastric malignant lymphoma. A thorough gastroscopic detection can help reduce misdiagnosis rate.
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