Objective This study aimed to investigate the effect of statins for plasma total cholesterol(TC) and low density lipoprotein-cholestero( LDL-C) , no-reflow phenomenon in patients with acute myocardial infarction who underwent percutaneous coronary interventional (PCI) therapy. Methods The blood samples were taken from the coronary artery in emergency PCI patients to determine TC and LDL-C. The patients who had undergone PCI therapy successfully were assembled into four groups, without statins therapy and without no-reflow phenomenon (group NSNN, n =88),without statins therapy and with no-reflow phenomenon (group NSN, n =19), with statins therapy and without no-reflow phenomenon (group SNN, n =52) ,with statins therapy and with no-reflow phenomenon (group SN, n = 2). The incidence of no-reflow and the plasma cholesterol, LDL-C were analyzed. Results No-reflow phenomenon occurred in 88 patients(54. 7%) of group NSNN, 19 patients(1l. 8%) of group NSN; 52 patients(32. 3%) of group SNN and two patients(1. 2%) of group SN. The rate of no-reflow phenomenon in the patients treated with statins was significantly lower than that of the patients treated without statins( P <0. 05). In the patients( NSNN, SNN) of no-reflow phenomenon, the plasma TC and LDL-C were significantly lower than those patients without no-reflow phenomenon( P 展开▼
