中国食管乳头状瘤临床特点分析

摘要

目的：总结我国食管乳头状瘤的临床特点，提高对本病的认识。方法通过中国医院知识数据库（CHKD），以“食管乳头状瘤”为关键词，对1979年1月至2012年11月发表的中文文章进行检索，提取其中有关食管乳头状瘤患者的临床资料并进行汇总分析。结果来自44家医院共1585例食管乳头状瘤患者进入本研究，男679例，女906例。发病年龄在14～79岁，平均年龄50岁。1430例单发，150例多发。205个病灶位于上段食管，650个病灶位于中段食管，695个病灶位于下段食管。1104个病灶直径≤1．0 cm，48个病灶直径＞1．0 cm。只有1例巨大食管乳头状瘤发生恶变。结论我国食管乳头状瘤患者的临床特点：女性多见，多为单发，体积通常在1．0cm以下，最常见于食管下段。巨大食管乳头状瘤或食管乳头状瘤病有恶变可能。%ABSTRACT:Objective To improve the recognition on esophageal papilloma (EP)by analyzing and summarizing the clinical features of EP in China.Methods All studies on EP published from Jan.1979 to Nov.2012 were retrieved in China Hospital Knowledge Database (CHKD).The clinical data of patients with EP were reviewed.Results A total of 1 585 patients with EP from 44 hospitals were enrolled,including 679 males and 906 females,with a mean age of 50 years (ranging from 14 to 79 years).There were 1 430 patients with a single lesion and 150 cases with multiple lesions.In terms of the location,205 lesions located at the upper esophagus,650 lesions at the middle esophagus and 695 lesions at the lower esophagus.1 104 lesions were equal or less than 1.0 cm in diameter,while the other 48 lesions were larger than 1 .0 cm.Canceration only happened in one case with a huge EP.Conclusion The clinical features of EP in our country show that EP typically happens in women more than men,mainly in single lesion with the size less than 1 .0 cm, and it mainly presents at the lower esophagus. Canceration may happen in EP or esophageal papillomatosis with giant size.