肥胖低通气综合征

摘要

With the improvement of living standards,fat people tend to be more and more.Obesity is becoming increasingly important in causing a series of related diseases such as hyperlipidemia,diabetes,respiratory diseases and so on.But obesity hypoventilation syndrome (OHS)which is easy to be ignored but has clinical significance can seriously affect the patient respiratory,cardiovascular and endocrine system.If OHS not timely corrected,the prognosis is poor,including respiratory failure,arrhythmia,heart failure and so on.This paper provides a review on OHS conception,pathogenesis,clinical manifestations and diagnostic criteria and treatment.OHS deserves more attention.%随着人们生活水平的提高,肥胖患者越来越多,因肥胖引起的一系列相关疾病如高脂血症、糖尿病、呼吸系统疾病等也越来越被重视。但其中最常被忽略又非常具有临床诊治意义的一种疾病是肥胖低通气综合征(obesity hypoventilation syndrome,OHS),可严重影响患者的呼吸、心脑血管及内分泌代谢系统,若不及时纠正,可进一步引发呼吸衰竭、心律失常、心功能衰竭等,预后恶劣。本文将就 OHS 的相关概念、发病机制、临床表现及最新诊治进展等方面的内容做逐一阐述,希望能引起相关临床医师的重视。