抑郁症和双相障碍认知损害比较和治疗策略

摘要

Cognitive impairment is a typical feature of mood disorders.Mood disorders include major depressive disorder (MDD) and bipolar disorder (BD).Cognitive impairment affects a patient's daily and social abilities.Therefore,in order to improve the quality of life,patients need to optimize their cognitive functions.In general,cognitive impairment develops as BD progresses,and cognitive impairment is more severe than depression.In this review,we discuss the differences of cognitive function in patients with MDD and BD.Four aspects were elaborated:① comparison of cognitive function of MDD and BD patients;② imaging identification of cognitive impairment;③factors affecting cognitive impairment;④ therapeutic strategies for improving cognitive function.%认知损害是心境障碍的典型特点.心境障碍包括抑郁症(MDD)和双相障碍(BD).认知损害影响患者的日常生活和社会能力,因此,为了提高生活质量,患者需要优化认知功能.而一般人群随着双相障碍进程,认知损害会逐渐进展,相比抑郁症来说认知损害更加严重.本文对抑郁症和双相障碍患者认知功能是否存在差异进行综述.从4方面进行阐述:①MDD和BD患者认知功能的比较;②认知障碍影像学鉴别;③认知障碍的影响因素;④改善认知功能的治疗策略.