海因酶和N-氨甲酰氨基酸水解酶的比例:由5-取代海因制备D-氨基酸的关键

摘要

The optically active D-amino areas are valuable intermediates for the production of semi-synthetic antibiotics; hormones, bioactive peptides, and 5-monosubstituted hydantoins are important precursors for the commercial production of aminoacids. Two enzymes are involved in the stereo-selective deavage of D, L-S-monosubstituted hydantoins and N-carbamoyl amino acid (Fig. 1).