1,25-二羟基维生素D对人大网膜脂肪细胞分化过程的作用

摘要

Objective To study the effects of 1,25 ( OH) 2 Vitamin D on human omentum majus lipocyte differentiation.Methods 1.25(OH)2Vitamin D were added to the cutture media of human omentum majus lipocyte.then the expression of trigiyceride and lipid droplet accumulation in the cytoplasm were recorded.Results 1.25 (OH)2 Vitamin D inhibited human omentum majus lipocyte differentiation.and synthesis of triglyceride.Conclusion This data advisory to obesitv balanced daily intake of Vitamin D.%目的 研究1,25-二羟基维生素D对人大网膜脂肪细胞分化过程的作用.方法 培养人大网膜脂肪细胞,在其生长的不同阶段加入1,25-二羟基维生素D,观察其对细胞的分化过程中的三酰甘油和细胞内脂肪积聚的作用.结果 1,25-二羟基维生素D 对人脂肪细胞的分化有抑制作用,并抑制三酰甘油的合成.结论 该研究结果可为肥胖人群人体合理地摄入维生素D提供理论指导.