重庆市中青年人高血压前期流行现状

摘要

Objective To investigate the prevalence and related risk factors of prehypertension among the adults of Chongqing area, so as to provide the basic data and theoretical basis for the primary prevention of hypertention and the cardiovascular and cere-brovascular events. Methods According to the data from the medical center of the first hospital affiliated to Chongqing Medical U-niversity in 2010, 20 000 effective samples aged 18 - 59 years from Chongqing area were analyzed. The prevalence was calculated and the relevant risk factors were analyzed by Logistic regression model. Results (l)Among 20 000 samples, prehypertension was in 7310 cases( 4968 males and 2342 females). The prevalence of prehypertension in Chongqing area was 36. 55%. (2) Compared with normal blood pressure group, BMI, waist-height ration(WHtR) , WC,TC, TG, LDL-C and blood sugar were higher in the pre-hypertension group, HDL-C was lower than that in the normal blood pressure group, showing statistical difference between the two groups. (3)The results of the logistic regression analysis showed that the related risk factors of prehypertension were age, BMI,WC, WHtR, TC, TG, HDL-C and blood sugar among men; and age, BMI, WC, WHtR, TC, TG and blood sugar among women. Both men and women,the high value of BMI was the most important high-risk factor,OR values were 1. 99(95 % confidence interval ,1. 80 - 2. 20) , 1. 82(95% confidence interval, 1. 58 - 2. 10) respectively. Conclusion Overweight and obesity are the most important influence factor of pre-hypertension. But the changes in blood lipids of the prehypertensive population should be paid attention to.%目的 分析重庆市中青年人高血压前期流行现状并探讨流行相关因素,为开展高血压的一级预防及对心、脑血管事件的防治工作提供基础资料和理论依据.方法 根据重庆医科大学附属第一医院体检中心2010年体检数据,获得18～59岁中青年人有效样本20 000例,计算人群中高血压前期患病率,分析正常血压、高血压前期、高血压人群相关指标差异,并应用Logistic回归模型进行危险因素分析.结果 (1)有效样本20 000例中,高血压前期7 310例,其中,男4 968例,女2 342例.高血压前期患病率为36.55%.(2)与正常血压组相比,肥胖测量指标体质量指数(BMI)、腰围/身高比(WHtR)、腰围(WC),代谢指标总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、血糖,高血压前期组均高于血压正常组,而高密度脂蛋白胆固醇(HDL-C)较血压正常组低,差异具有统计学意义.(3) Logistic回归分析显示,年龄、BMI、WC、WHtR、总胆固醇、三酰甘油、血糖是男性高血压前期患病的危险因素,HDL-C是保护因素;年龄、BMI、WC、WHtR、总胆固醇、三酰甘油、血糖是女性高血压前期患病的危险因素.其中,BMI对男性高血压前期和女性高血压前期患病影响均达到了最大,优势比(OR)值分别为1.99(95% CI 1.80～2.20)、1.82(95% CI 1.58～2.10).结论超重和肥胖是高血压前期最重要的影响因子,同时也要重视高血压前期人群的血脂变化.