高龄因素对EST治疗胆总管结石的Logistic分析

摘要

Objective To explore the effect of aging factor on the outcome of endoscopic sphincterotomy (EST ) in treating common bile duct stones .Methods 60 cases of EST treated in this hospital from January 2004 to December 2011 were selected .Among them ,30 cases were more than 60 years old as the aged group and 30 cases were less than 60 years old as the control group .The single-factor Logistic regression analysis was performed to investigate the influence of aging factor on the EST effect and its compli cations .rnResults Among 30 aged cases ,28 cases were performed once EST with the successful rate of 93 .33% .The occurrence rate of complications was 16.67%.In the control group ,the successful rate of once EST was 90 .00% and the complication occurrence rate was 13 .33% .The logistic analysis of once successful rate in the two groups showed OR=0 .964 ,95% CI:0 .912-1.019 (P= 0.198).The single factor logistic analysis of postoperative complications in the two groups showed OR= 1.024 ,95% CI:0.978-1.056(P=0 .462) .Conclusion Aging is not a risk factor for the successful rate of stone removal in once EST and postoperative complications .EST is safe and effective for the elderly patients with common bile duct stone .%目的 探讨高龄因素对内镜十二指肠乳头括约肌切开术(EST)治疗胆总管结石的影响.方法 选择该院2004年1月至2011年12月经EST治疗胆总管结石的患者60例,其中年龄大于60岁的患者30例(高龄组);年龄小于60岁的患者30例(对照组).通过单因素Logistic回归分析高龄因素对手术效果及并发症的影响.结果 30例高龄患者共28例经1次EST取净结石,成功率为93.33%;高龄组手术并发症的发生率为16.67%.30例对照组患者1次EST取净结石成功率为90.00%,并发症发生率为13.33%.对高龄组和对照组的1次取石成功率进行单因素Logistic分析结果提示:OR=0.964,95%CI:0.912~1.019 (P=0.198).对高龄组和对照组术后并发症进行单因素Logistic分析结果提示:OR=1.024,95%CI:0.978~1.056(P=0.462).高龄患者在1次EST取石成功率以及术后并发症方面与对照组比较,差异无统计学意义(P＞0.05).结论 高龄不是EST 1次取石成功率及术后并发症的危险因素,EST对于高龄患者是安全有效的.