饮酒对宜昌市职业人群代谢综合征患病率及其相关因素的影响

摘要

Objective To study the relationships of alcohol consumption to the prevalence of metabolic syndrome and its re‐lated components in Yichang professional population and provide decision making basis for lifestyle intervention to MS crowd in the city .Methods We examined baseline data from 3 640 participants (2 285 men and 1 355 women) aged 20 to 70 years who under‐went a careful drinking habits survey ,then physical examination and blood chemical examination .They were divided into three groups by average ethanol intake [non ,occasional (<10 g/day) ,moderate (≥10 and <30 g/day) ,and heavy (≥30 g/day) drink‐ers] .Results Compared with no drinking and occasional drinking group ,the prevalence of MS and abnormal rate of BMI ,DBP ,TG , UA increased significantly (P< 0 .05) while SBP decreased significantly in moderate drinking group;compared with moderate drinking group ,the prevalence of MS and abnormal rate of BMI ,DBP and SBP ,GLU ,TCH ,TG ,LDL C ,UA increased significantly (P<0 .05) in heavy alcohol consumption group;whether moderate or heavy drinking ,abnormal rate of CRP and HDL C did not change significantly(P>0 .05) .Conclusion Even moderate drinking has a significant effect to BMI ,DBP ,TG ,LDL C ,UA ,but not obvious to CRP ,GLU ,TCH ,HDL C .Excessive alcohol consumption has a very bad effect on BMI ,DBP ,SBP ,GLU ,TCH ,TG , HDL C ,LDL C ,UA .Both the prevalence of MS and the abnormal rate of its related components are proportional to the alcohol in‐take .Although moderate drinking could lower SBP and GLU ,but can not reduce the incidence of MS .%目的：研究饮酒对宜昌市职业人群代谢综合征（MS）患病率及其相关因素的影响，为该市MS人群生活方式干预提供决策依据。方法抽样调查宜昌市15个单位职业人群共3640人（男2285人，女1355人，年龄20～70岁），详细询问其饮酒习惯并填写调查表，进行体格检查和实验室检查，根据日饮酒量分为3组（不饮和偶尔饮酒组、适量饮酒组、过量饮酒组），对结果进行统计分析。结果与不饮和偶尔饮酒组比较，适量饮酒组MS患病率及体质量指数（BMI）、舒张压（DBP）、三酰甘油（TG）、尿酸（UA）异常率显著升高（P＜0．05），收缩压（SBP）异常率显著下降（P＜0．05）；过量饮酒组BMI、DBP、SBP、葡萄糖（GLU）、总胆固醇（TCH）、TG、低密度脂蛋白胆固醇（LDL‐C）、UA、MS患病率显著升高（P＜0．05）。与适量饮酒组比较，过量饮酒组MS患病率及BMI、DBP、GLU、TCH、TG、LDL‐C、UA异常率上升显著（P＜0．05）。不论适量还是过量饮酒，C‐反应蛋白（CRP）及高密度脂蛋白胆固醇（HDL‐C）异常率没有显著变化（P＞0．05）。结论适量饮酒对宜昌市职业人群BMI、DBP、TG、LDL‐C、UA有显著影响，对GLU、TCH、HDL‐C、CRP影响不明显。MS患病率及其相关因素异常率与乙醇摄入量呈正相关。适量饮酒有降低SBP和GLU作用，但不能降低MS发病率。