Peptu00cddeos antigu00canicos inducers of antibodies specific for identification of modifications of the greater prevalence of subtype 2B von Willebrand disease factor and normal

摘要

Peptu00cddeos antigu00canicos inducers of antibodies specific for identification of modifications of the greater prevalence of subtype 2B von Willebrand disease factor and normal.This invention comprises the application of synthetic peptides to obtain antiserum and specific antibodies for the identification of changes of higher prevalence of subtype 2b of the DVW and for identifying and quatificau00e7u00e3o of von Willebrand factor in normal human with utility Daignu00f3stico, classification of von Willebrand disease in studies of quatificau00e7u00e3o and binding to factor VIII.In addition, the invention establishes specific process for the preparation of conjugates with the carreador protein, keyhole limpet hemocyanin, immunization in mice and purification of these antibodies.