Valproate-Induced Type I von-Willebrand Disease - a Common Occurrence?

摘要

An increased bleeding tendency and its possible consequences have a considerable impact on the lives of the people concerned. This is shown by restrictions in daily life, e.g. in sports activities, by the increased risk associated with operative procedures or accidents but also by the necessary treatment measures.If the disturbances of the coagulation system are a consequence of drug therapy, a careful benefit-to-risk assessment is called for. For a responsible decision comprehensive data on the drug concerned are essential.