慢性消化性溃疡生命质量及患者报告结局的影响因素分析

摘要

Objective To analyze the quality of life and its influence factors in patients with peptic ulcer.Methods The SF-36 was used to survery 120 patients with peptic ulcer.The QOL scores at different levels of some factors including gender,age,na-tionality,occupation,marriage,medical forms,economic,cultural level,treatment method and clinical type were compared by meth-ods of two sample t-test and analysis of variance.Results Peptic ulcer patients′scores in the domain of RE,PF,RP,BP,GH,VT, SF,RE,PCS and MCS are lower than that of the normal,exception of the domain of MH(P <0.05).The differences were statisti-cally significant.Six factors can be influenced some domain or total score of the scale(P <0.05)and the differences were statistical-ly significant.Conclusion Find out the influencing factors on peptic ulcer patients′quality of life can be provided the basis for clini-cal treatments.%目的：对慢性消化性溃疡（PU）患者进行生命质量测评，分析影响患者生命质量的因素。方法采用普适性量表———健康状况调查问卷（SF-36）作为调查工具，对120例 PU 住院患者生命质量进行测评。利用两独立样本 t 检验对患者的生命质量得分和全国常模进行比较。利用两独立样本 t 检验和方差分析，分别对不同性别、年龄、民族、职业、婚姻、医疗形式、经济状况、文化程度、治疗方法、临床类型的各领域得分进行比较分析。结果PU 患者除了精神健康（MH）领域之外其余7个领域以及躯体综合总分（PCS）、心理综合总分（MCS）得分均低于健康对照组，差异有统计学意义（P ＜0．05）；性别、年龄、经济状况、文化程度、医疗形式和治疗方法对 SF-36量表某些领域或者综合总分有影响，差异均有统计学意义（P ＜0．05）。结论找出影响 PU患者生命质量的因素，为今后临床治疗提供基础。