全身抚触联合双歧杆菌四联活菌片对早产儿喂养不耐受及生长发育的影响

摘要

Objective To investigate the effect of combining Bifidobacterium quadruple viable piece with body massage on preterm infants'feeding intolerance and early development.Methods From January 2010 to October 2013 92 preterm infants needing intermittent tube feeding were admitted in neonatal wards in Jinxiang Hospital Affiliated to Jining Medical College.They were randomly divided into treatment group and control group with 46 in each.The treatment group was provided with body massage combined with Bifidobacterium quadruple viable piece, and the feeding intolerance and development related indexes were recorded.Results Seven days after treatment, the effective rate of feeding intolerance was 76.1% ( 35/46 ) in the treatment group and 43.5% ( 20/46 ) in the control group, respectively.The difference was significant (χ2 =10.18, P<0.05).Compared with the control group, the breastfeeding initiation was earlier, the initiation quantity was larger, and the time for whole gastrointestinal feeding through mouth was shorter in the treatment group ( t value was 4.79, 4.82 and 4.11, respectively, all P<0.05) .The time return to birth weight was remarkably shorter but the extent of head circumference increase and the body weight at 14 d were greater in the treatment group than the control group ( t value was 5.16, 3.65 and 5.04, respectively, all P<0.05).Conclusion The body massage combined with Bifidobacterium quadruple viable piece has an important influence on feeding intolerance of preterm infants.It can promote gastrointestinal mature, reduce the occurrence of feeding intolerance symptoms, and promote infants’ growth and development.%目的：探讨联合双歧杆菌四联活菌片的全身抚触对早产儿喂养不耐受及前期生长发育的影响。方法选择2010年1月至2013年10月在济宁医学院附属金乡医院新生儿病房收治的需间断胃管喂养的早产儿92例，随机分为治疗组和对照组各46例，治疗组除常规治疗外予以全身抚触联合双歧杆菌四联活菌片，记录两组喂养不耐受和生长发育相关指标。结果治疗7天后，喂养不耐受治疗的有效率，治疗组为76．1％（35/46），对照组为43．5％（20/46），差异具有统计学意义（χ2＝10．18，P＜0．05）；治疗组的开奶时间少于对照组，治疗组的开奶量高于对照组，治疗组达到经口全胃肠喂养时间少于对照组，差异均具有统计学意义（t值分别为4．79、4．82、4．11，均P＜0．05）。治疗组恢复至出生体重的时间显著短于对照组，而头围增长幅度以及14天时体重量显著大于对照组（t值分别为5．16、3．65、5．04，均P＜0．05）。结论全身抚触联合双歧杆菌四联活菌片对早产儿喂养不耐受及生长发育具有重要影响，能够促进胃肠功能成熟，显著降低喂养不耐受症状的发生，并对其生长发育具有促进作用。