43例穿透性粥样硬化性主动脉溃疡随访观察

摘要

Objective To investigate the feasibility of the volume of penetrating atherosclerotic aortic ulcer (PAU) as a marker of disease progression. Methods The treatment and follow-up data of 43 cases of penetrating atherosclerotic aortic ulcer without surgical indication from January 2011 to June 2015 in our hospital were retrospectively analyzed. The change of PAU volume were observed by CT angiography. Results Seven patients developed lesions progression and underwent endovascular repair. The maximum PAU volume of the operation group was (1.21±0.07) cm3, and the non-operation group was (0.84±0.14) cm3. The difference was statistically significant(P<0.001). Conclusion The volume of PAU is associated with the progression of the disease, which predicts progression of atherosclerotic aortic lesions in patients.%目的 探讨穿透性粥样硬化性主动脉溃疡(PAU)容积作为病情进展指标的可行性.方法 回顾性分析2011年1月至2015年6月,我院诊治的无外科干预指征的43例PAU患者的药物治疗及随访资料,观察随访期内CT血管造影显示的PAU容积变化情况.结果 7例患者主动脉溃疡病变出现进展,接受主动脉腔内修复手术.手术组首诊时最大PAU容积为(1.21±0.07)cm3,非手术组为(0.84±0.14)cm3,两者差异有统计学意义(P<0.001).结论 PAU的容积与病情进展相关,它可以预测患者粥样硬化性主动脉溃疡病变是否进展.