Objective Toinvestigate the influence of high altitude hypoxia on left ventricular function in anti-seismic soldiers using wave intensity technology. Methods According to the time of entering into Yushu of Qinghai province,250 anti-seismic soldiers were divided into the first group(100 cases,rushed into plateau in 7 days)and the second group(150 cases, stayed there one year and more) ,left ventricular ejection fraction (LVEF) .fraction shortening (FS) , the ratio of peak early diastolic velocity and late diastolic velocity of mitral flow(E/A) were detected by conventional echocardiagraphy . The magnitude of W1 and W2,and the length of R-lst interval as well as lst-2nd interval were recorded by Wave Intensity technology, and compared with the healthy Officers and soldiers in plain. Results Compared with control group, Wl of the first group decreased , but there was no statistical significance, Wl of the second group decreased(P<0. 05) ;the data of W2 and lst-2nd interval of two groups were lower (P<0. 05), the data of LVEF, FS.E/A and R-lst intervalof two groups had no significant different from control group. Conclusions WI may be used to evaluate the left ventricular systolic and diastolic function in anti-seismic soldiers at high altitude.%目的 应用瞬时波强(WI)技术探讨高原低氧环境对抗震官兵左心室功能的影响.方法 根据进入青海玉树地区时间的不同,将252例抗震官兵分为2组:第1组(100例,急进高原7d内),第2组(152例,留居高原1年及以上).常规超声心动图检测左室射血分数(LVEF),左室短轴缩短率(FS),二尖瓣血流舒张早期峰值流速与舒张晚期峰值流速的比值(E/A);应用WI技术测量第1个正向波搏幅大小(W1)、第2个正向波搏幅大小(W2)、R-1st间期及2个正向波之间的时间(1st-2nd)间期,并与平原健康官兵进行对比分析.结果 与对照组比较,第一组W1稍减低,但结果无统计学意义,第二组W1减低(P<0.05);两组W2均减低,1st-2nd均缩短(P<0.05),两组LVEF、FS、E/A及R-1st与对照组比较差异无统计学意义(P>0.05).结论 WI可成为敏感评价高原缺氧状态下抗震官兵左心室舒缩功能的一项有价值的指标.
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