胰腺导管内乳头状黏液性肿瘤的声像图分析

摘要

Objective To analyze the clinical and ultrasonographic features of intraductal papillary mucinous neoplasm (IPMN) of the pancreas and to assess the usefulness of transabdominal ultrasonography. Methods Twelve patients with IPMN underwent surgery, including 4 (33.3%)with adenoma and 8(66.7%) with adenocarcinoma. IPMN was classified into 3 categaries by the site of main duct,branch duct and combined type based on the ultrasonographic findings preoperatively. All the clinical presentations and the ultrasonographic imaging findings were analyzed and compared with the histologic diagnosis. Results Of malignant IPMNs,diabetes was presented in 5 cases,elevated CA19-9 was presented in 4 cases and steatorrhea was presented in 2 cases. But these was not presented in benigns. Transabdominal ultrasonography revealed all the cystic or cystic-solid lesions in this study. The mean diameter of the lesions with adenoma was (1.4 ± 0.8)cm (range,0.5 - 2.0 cm) and that with adenocarcinoma was (6.3 ± 6.0)cm (range, 2.0 - 20 cm). The mean diameters of the main duct for the cases with adenomas and adenocarcinomas were (1.0 ± 0.8) cm and ( 1.6 ± 1.0) cm, respectively. Among the adenomas, 3 cases were calssified as branch type and 2 were demonstrated with mural nodules and no colour signals was detected within them. Five of the malignancies were considered as main duct type and 3 were combined type. Seven cases were detected mural nodules and showed abundant colour flow signals within them. Conclusions Transabdominal ultrasonography revealed the pancreatic cystic lesions and dilated ducts of IPMN. Some characteristics should be considered for malignancy: clinical symptoms, tumor size and mural nodules with colour flow signals,which may be helpful for the diagnosis and management of IPMN.%目的 分析胰腺导管内乳头状黏液性肿瘤的临床及声像图特点,探讨经腹超声对本病的应用价值.方法 回顾性分析12例经手术病理证实的胰腺导管内乳头状黏液性肿瘤的病例资料,其中黏液腺瘤4例,黏液腺癌8例.依据病灶发生部位将其分为三种类型:主胰管型、分支胰管型和混合型,对照组织病理学结果总结其临床及声像图表现.结果 恶性者中临床症状较重,5例伴有糖尿病,2例有脂肪泻表现,4例伴有CA19-9升高,而良性者仅表现为上腹不适、腹痛等.超声显示病灶呈囊性或囊实性,良性病灶平均(1.4±0.8)cm,主胰管平均直径(1.0±0.8)cm,其中分支导管型3例(75%),主胰管型1例(25%);2例可见附壁结节,未见明确血流信号.恶性病灶平均(6.3±6.0)cm,主胰管平均直径(1.6±1.0)cm主胰管型5例(62.5%),混合型3例(37.5%),未见分支导管型;7例(7/8,87.5%)可见附壁结节,5例结节内测及较丰富的血流信号.结论 经腹超声可显示胰腺导管内乳头状黏液性肿瘤的病变特点,即囊性或囊实性病灶及扩张的胰管,结合患者的临床症状及超声所显示的病灶大小、结构及血流信号等可进一步提示其良恶性.