脊神经根病变的病因和治疗特征

摘要

目的:脊神经根病是骨科的常见病,以脊神经支配区域疼痛为主要临床表现,致病因素复杂,临床上根据不同的病因,选择手术或非手术治疗.文章回顾了近几年的研究报告,主要阐述脊神经根病的病因和治疗特征.资料来源:应用计算机检索Medline数据库1990-01/2004-08期间的相关文章,检索词"nervi spinales,ain,herapy",限定文章语言种类为英文.同时计算机检索中国期刊全文数据库、万方数据库1990-01/2004-12期间的相关文章,检索词"脊神经,疼痛,治疗",限定文章语言种类为中文.资料选择:选择有关脊神经根病的病因、发病机制和治疗的文?均为研究原著.资料提炼:共收集到22篇近5～14年有关脊神经根病的病因与发病机制、手术治疗、微创与介入治疗、非手术治疗的特征等方面的文献.资料综合:脊神经根病以颈腰背痛最为多见,由各种病因所致对脊神经根的机械性压迫和化学性物质刺激而诱发本病,临床上根据不同的病因,选择手术或非手术治疗.所以对脊神经根病的病因和治疗特征必须有足够的认识.结论:检索的文献报告表明,对脊神经根病的病因做出正确判断并制定相应的治疗方案,是保证有效治疗的关键.%OBJECTIVE: Radiculopathy is a common disease in orthopedics,clinically manifested chiefly by pains in the regions innervated by the spinal nerve involved. Since the etiology is complex,either surgical or non-surgical interventions can be adopted accordingly. This study reviewed recent relevant reports to explore the etiology and therapy of radiculopathy.DATA SOURCES: A computer-based search were carried out in Medline database for related articles published between January 1999 and August 2004 using the key words of "nervi spinales,pain,therapy" with language of the text limited to English. A computer-based search of Chinese periodical database,Wanfang Digital Database was also conducted for articles published in Chinese between January 1999 and December 2004 with the same searching words in Chinese language.STUDY SELECTION: Original studies of the etiology,pathogenesis and treatment of radiculopathy.DATA EXTRACTION: Totally 22 articles related to the etiology,pathogenesis,surgical treatment,minimal invasive and interventional treatment,as well as non-surgical treatment for radiculopathy were collected.DATA SYNTHESIS: Cervical,lumbar and back pains are the most common clinical manifestations of radiculopathy,induced by mechanical compression and chemical stimulation due to different etiologies. In clinical practice,surgeries or alternative non-surgical treatment can be adopted according to the etiology,the choice of which depends on,therefore,a thorough knowledge of the etiology and therapy of radiculopathy.CONCLUSION: The key for achieving favorable outcome of the patients with radiculopathy lies in correct recognition of the etiology and proper therapeutic decisions.