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Tensile properties of spinal nerve roots at high strain rates: An in vivo study.

机译:高应变速率下脊神经根的拉伸特性:一项体内研究。

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摘要

Spinal nerve roots are subject to tension in many traumatic and non-traumatic situations, such as motor vehicle accidents or disc herniation. These events may cause severe injuries and pain to the victims who are involved. By obtaining a better understanding of the biomechanical properties of spinal nerve roots, in particular in tension, better methods can be developed to help predict the amount of tension that may be applied to spinal nerve roots before causing serious injury to an individual.;For this study biomechanical properties of dorsal nerve roots at the L4 and L5 lumbar levels were determined at high displacement rates of 20, 200, and 800 mm/sec. The study was done using Sprague Dawley rats in vivo. Load and displacement data was obtained from the nerve roots as they were stretched to failure. Maximum load, maximum stress, and modulus of elasticity (E) values were calculated.;Maximum load values of 8.3 +/- 2.3g, 21.4 +/- 5.1g, and 26.3 +/- 4.2g were found for the 20, 200, and 800 mm/sec rates, respectively. Also, maximum stress and E values of 210.1 +/- 42.0 kPa and 1.1 +/- 0.3MPa, 511.5 +/- 85.2 kPa and 3.1 +/- 1.4MPa, and 687.9 +/- 120.6 kPa and 3.5 +/- 1.3MPa were obtained for the 20, 200, and 800 mm/sec rates, respectively. It was found that as the displacement rate increased, the maximum load, stress, and E values also increased. No significant difference was shown in the failure strain among the three displacement rates.;The results from the study demonstrated spinal nerve roots exhibit a strain rate dependency. These results help give a better understanding of how tensile properties of nerve roots are affected by different strain rates.
机译:在许多创伤性和非创伤性情况下,例如汽车事故或椎间盘突出症,脊神经根都会承受张力。这些事件可能会对所涉受害者造成严重伤害和痛苦。通过更好地了解脊神经根的生物力学特性,尤其是在张力方面,可以开发出更好的方法来帮助预测在对个人造成严重伤害之前可能施加于脊神经根的张力量。研究人员在20、200和800 mm / sec的高位移速率下确定了L4和L5腰椎水平的背神经根的生物力学特性。该研究是在体内使用Sprague Dawley大鼠完成的。从神经根拉伸至衰竭时获得载荷和位移数据。计算了最大载荷,最大应力和弹性模量(E)值;发现20、200的最大载荷值分别为8.3 +/- 2.3g,21.4 +/- 5.1g和26.3 +/- 4.2g和800 mm / sec的速度。同样,最大应力和E值分别为210.1 +/- 42.0 kPa和1.1 +/- 0.3MPa,511.5 +/- 85.2 kPa和3.1 +/- 1.4MPa,687.9 +/- 120.6 kPa和3.5 +/- 1.3MPa分别以20、200和800 mm / sec的速度获得图像。发现随着位移率的增加,最大载荷,应力和E值也增加。三种位移率之间的破坏应变没有显着差异。研究结果表明,脊神经根表现出应变率依赖性。这些结果有助于更好地理解神经根的拉伸特性如何受到不同应变速率的影响。

著录项

  • 作者

    Yaldo, Joseph M.;

  • 作者单位

    Wayne State University.;

  • 授予单位 Wayne State University.;
  • 学科 Engineering Biomedical.;Biophysics Biomechanics.
  • 学位 M.S.
  • 年度 2012
  • 页码 99 p.
  • 总页数 99
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-17 11:43:01

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