BACKGROUND:Percutaneous vertebroplasty and percutaneous bal oon kyphoplasty can effectively treat osteoporotic compression fracture, but which method is better stil controversial in China.n OBJECTIVE:To compare clinical efficacy and safety of percutaneous vertebroplasty and percutaneous bal oon kyphoplasty for osteoporotic compression fracture. n METHODS:Pubmed, Springer and Wanfang Database were retrieved by computer. Relevant Chinese and English journals were retrieved by hand. In accordance with inclusion and exclusion criteria, literatures concerned the comparison of curative effects of percutaneous vertebroplasty and percutaneous bal oon kyphoplasty for osteoporotic compression fracture were searched. RevMan 5.0 software provided by Cochrane was used to statistical y analyze the data. n RESULTS AND CONCLUSION:Total y 10 literatures were included in accordance with the inclusion criteria, including 1 literature of randomized control ed trials, and 9 literatures of prospective cohort study. Meta-analysis results demonstrated that no significant differences in operation time, long-period visual analogue scale were detected. Compared with the percutaneous vertebroplasty group, anterior vertebral height was higher in the percutaneous bal oon kyphoplasty group. Thus, incidence of cement leakage and long-period kyphotic angle decreased. These results indicated that compared with percutaneous vertebroplasty, percutaneous bal oon kyphoplasty can diminish long-period kyphotic angle, increase anterior vertebral height and reduce incidence of cement leakage.%背景：经皮椎体成形和经皮球囊扩张椎体后凸成形均可有效治疗骨质疏松性压缩骨折，但具体采用哪种方法，国内外仍存在争议。n 目的：比较球囊后凸成形与经皮椎体成形治疗骨质疏松性腰椎压缩性骨折的临床疗效和安全性。n 方法：计算机检索 PubMed，Springer 以及万方等数据库，手工检索相关的中英文骨科杂志。按照既定的纳入和排除标准查找有关后凸成形术与经皮椎体成形术治疗骨质疏松性椎体压缩骨折疗效进行比较的文献。利用Cochrane协作网提供的RevMan5.0软件进行统计学分析。n 结果与结论：共纳入符合标准的文献10篇，其中随机对照研究1篇，前瞻性队列研究9篇。Meta分析结果显示：两种方法操作时间、治疗后长期疼痛目测类比评分比较差异均无显著性意义。与经皮椎体成形组相比，椎体后凸成形组可以更好地增加椎体前缘高度，降低骨水泥渗露的发生率，以及减小远期后凸角。表明与经皮椎体成形相比，经皮球囊扩张椎体后凸成形可以更好地减小远期后凸角，增加椎体前缘高度，降低骨水泥渗露率。
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