应用阴离子交换树脂有效合成3-芳氨基-4-氰基-5-氨基吡唑

摘要

研究了不活泼芳胺(杂环胺)与α,α-二氰基二硫缩醛的加成-消除反应.报道了一种应用阴离子交换树脂有效合成3-芳氨基-4-氰基-5-氨基吡唑的一锅煮方法.%The addition-elimination reaction of inactive aromatic amine with α, α-dicyano ketene dithioacetals has been studied. An efficient one-pot method for the synthesis of 3-arylamino-4-cyano-5-aminopyrazole mediated with anion exchange resin (D261) is described.