新型2-甲氧羰基-5-芳甲亚胺基苯磺酰胺的合成及其生物活性

摘要

在微波或超声波辅助下,2-甲氧羰基-5-氨基苯磺酰胺与取代苯甲醛反应合成了8个新型2-甲氧羰基-5-芳甲亚胺基苯磺酰胺(3a ～ 3h),其结构经1H NMR,MS及元素分析表征.生物活性测试结果表明,大部分3具有一定的杀菌活性,其中3b和3f在用量为500 mg·L-1时,对黄瓜菌核病的防治效果高于90％.%Eight novel 2-methoxycarbonyl-5-arylazomethine benzenesulfonamides(3a ~3h) were syn thesized by the reaction of 2-methoxycarbonyl-5-amine-benzenesulfonamide with substituted phenylal dehyde under microwave irradiation or ultrasonic irradiation. The structures were characterized by H NMR, MS and elemental analysis. The preciminary bioactivity tests showed that 3b and 3f exhibi ted more than 90% activities against Sclerotinia sclerotiorum(lAb. ) de Bary at 500 mg ? L-1.