Objective To study the effects of Dezocine on pain in patients following laparoscopic cholecystectomy and during postoperative recovery pe⁃ riod. Methods All 120 patients with laparoscopic cholecystectomy were randomly divided into observation group and control group,60 cases in each group. Both groups of patients were given general anesthesia. About 30 minutes before the end of the operation, 0.1 mg/kg of intravenous dezocine injection were given to the obser⁃vation group while the same dose of saline was given to the control group. The recovery time and extubation time and VAS score were compared between two groups. Results As compared with the control group,the recovery time and extubation time were not significantly different(P>0.05). In the observation group VAS scores in anes⁃thesia recovery after 0.5 h, 1 h, 2 h and 4 h were respectively 2.91+0.52, 2.53+0.30, 1.91+0.29 and 1.54+0.37, which were lower than those in the control group [(4.61+0.61), (3.69+0.49), (3.02+0.41) and (2.81+0.38)], with statistically significant differences (P<0.05). In the observation group after wake up immediately and emer⁃gence of 10min, 20min, 30min, the restlessness scores were respectively 1.91+0.52, 1.62+0.49, 0.91+0.45 and 0.37+0.16, which were lower than those in the control group [(2.46+0.56), (2.15+0.44), (1.96+0.52) and (1.01+0.39)], with statistically significant differences(P<0.05). In the control group, 8 cases had adverse reactions with the incidence rate being 13.33%. In the observation group there were 2 cases with adverse reactions with the incidence rate being 3.33%. The adverse reaction rate of the observation group was lower than that in the control group(P<0.05). Conclusion Preventive intravenous injection of Dezocine will not affect the anesthe⁃sial effect of peritoneoscopic gallbladder excision surgery but can effectively relieve postoperative pain,and im⁃prove the recovery of patients with agitation and adverse reactions.%目的：探究地佐辛对腹腔镜胆囊切除术复苏期及术后疼痛的影响。方法：腹腔镜胆囊切除术患者120例，按随机数字表法分为观察组和对照组各60例。均给予常规麻醉，手术结束前30 min，观察组以0.1 mg/kg的剂量静脉注射地佐辛，对照组注射同等剂量的生理盐水。比较两组麻醉苏醒时间和拔管时间，麻醉苏醒后VAS评分，苏醒后躁动程度评分和不良反应。结果：与对照组相比，观察组苏醒时间与拔管时间没有明显差异（P＞0.05）；观察组在麻醉苏醒后的0.5 h、1 h、2 h、4 h时的VAS评分分别为（2.91±0.52）、（2.53±0.30）、（1.91±0.29）、（1.54±0.37）分，均低于对照组的（4.61±0.61）、（3.69±0.49）、（3.02±0.41）、（2.81±0.38）分，差异有统计学意义（P＜0.05）。观察组在苏醒即刻及苏醒后10 min、20 min、30 min时的躁动程度评分分别为（1.91±0.52）、（1.62±0.49）、（0.91±0.45）、（0.37±0.16）分，均低于对照组的（2.46±0.56）、（2.15±0.44）、（1.96±0.52）、（1.01±0.39）分，差异有统计学意义（P＜0.05）。对照组8例出现不良反应，发生率为13.33%；其中3例恶心，2例呕吐，2例头晕，1例寒战。观察组2例出现不良反应，发生率为3.33%；其中1例恶心，1例呕吐。观察组不良反应率比对照组有所降低（P＜0.05）。结论：预防性静脉注射地佐辛，不会影响腹腔镜胆囊切除术麻醉效果，可有效缓解术后疼痛，改善复苏期躁动与不良反应的发生率。
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