cqvip:A new Schiff base compound, 2-bromo-4-chloro-6-[(4-methylpyridin-2-ylimino)me- thyl]phenol (C13H10BrClN2O), has been synthesized by the condensation of equimolar 3-bromo-5- chlorosalicylaldehyde and 4-methylpyridin-2-ylamine in a methanol solution. The compound was characterized by elemental analysis, IR spectra, and single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group P21 with a = 6.048(3), b = 14.063(7), c = 7.623(4) , β = 97.703(7)o, Z = 2, V = 642.5(6) 3, Dc = 1.683 g/cm3, Mr = 325.59, λ(MoKα) = 0.71073, μ = 3.395 mm-1, F(000) = 324, R = 0.0370 and wR = 0.0662. A total of 3879 reflections were collected, of which 1970 with I > 2σ(I) were observed. As expected, the molecule adopts a trans configuration about the C=N double bond. The benzene and pyridine rings are nearly coplanar (mean deviation from the combined plane is 0.031(3) ), with their dihedral angle of 3.3(3)o. The preliminary biological tests show that the compound has excellent antibacterial activities.
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