4周运动减肥对肥胖青少年血浆致动脉粥样硬化指数和脂酰辅酶A胆固醇酰基转移酶2的影响

摘要

Objective To observe the effect of weight reduction on plasma atherogenic index and cyl-coenzyme A cholesterol acyltransferase 2 (ACAT2) of obese adolescents. Methods 30 obese adolescents took part in 4-week aerobic exercise and diet program for weight reduction. Results After 4 weeks of exercise and diet,the body weight,fat percentage,BMI and serum insulin of the subjects reduced significantly(P < 0.01);the level of LPL and the ratio of HDL-C/LDL-C increased and the level of TG, TC,HDL-C,LDL-C,atherogenic index and ACAT2 decreased significantly (P < 0.01). Conclusion Weight reduction through exercise and proper diet effectively improves somatometric measurements,lipid metabolism and insulin resistance to a certain extent in obese adolescents.%目的:观察运动减肥对肥胖青少年血浆致动脉粥样硬化指数和脂酰辅酶A胆固醇酰基转移酶等动脉粥样硬化致病相关因子的影响.方法:以参加2011年上海巅峰运动减肥夏令营的30名肥胖青少年为对象,进行4周中小强度有氧运动为主结合适当饮食控制的减肥运动训练.分别于入营第一天和出营前一天进行身体形态及血液指标测试.结果:经过夏令营4周有氧运动训练,肥胖青少年体重、体脂率、BMI与运动前相比显著下降,空腹血清胰岛素、血脂水平与运动前相比均明显改善,血浆致动脉粥样硬化指数、脂酰辅酶A胆固醇酰基转移酶2水平显著降低.结论:4周有氧运动明显降低了肥胖青少年的肥胖程度和胰岛素水平,改善血脂代谢,在一定程度上降低了动脉粥样硬化发病的风险.