负重对帕金森病患者上肢肌群表面肌电信号的影响

摘要

目的：观察帕金森病（PD ）患者上肢无负重和负重情况下上肢肌群表面肌电信号变化特征。方法：26例帕金森病患者为PD组，28例正常人作对照组，在坐位上肢屈肘无负重和负重1．5kg的静态运动负荷下，采用表面肌电对肱二头肌及屈腕肌群进行线性时、频分析。结果：PD组中位频率（MF）和平均功率频率（MPF）均值高于对照组（P＜0．01），而平均肌电值（AEMG）值显著低于对照组（P＜0．01）。PD组的肱二头肌MF值、MPF值均小于屈腕肌群（P＜0．05，0．01）；PD组无负重的MF和MPF均值均大于负重时（P＜0．05，0．01），而无负重时的AEMG小于负重时（P＜0．01）；无负重时肱二头肌的MF均值、MPF均值均小于屈腕肌群（P＜0．05，0．01）。结论：帕金森病患者上肢肌群运动单位募集过度，肌力下降，其中以前臂肌群或上肢无负重时最明显，表面肌电信号可以反映帕金森病患者的肌肉功能。%Objective :To observe changes and characteristics of the surface electromyogram (sEMG) signals of the upper limb muscles in Parkinson's disease (PD) patients without or with load .Methods:Twenty-six PD patients (PD group) and 28 healthy individuals (control group) were enrolled in this study .All the subjects were subjected to isometric contraction for elbow flexion with no load or 1 .5 kg load .The surface myoelectric signals of biceps brachii and wrist flexion muscles were collected and processed by linear time- and frequency-domain method .Re-sults :The median frequency (MF) and mean power frequency (MPF) in PD group were higher than in control group (P< 0 .01) .The value of average electromyography (AEMG) in PD group was obviously lower than in control group (P<0 .01) .The values of MF and MPF of biceps brachii in the PD group were lower than those of wrist flex-ion muscles (P<0 .05 ,or P<0 .01) .The MF and MPF in PD group with no load were higher than those in PD group with load (P<0 .05 ,or P<0 .01) ,and the value of AEMG in the presence of load was lower than that in the absence of load (P<0 .01) .In the absence of load ,MF and MPF of biceps brachii were lower than those of wrist flexion muscles (P<0 .05 ,or P<0 .01) .Conclusions:The motor units of the upper limb muscles in PD patients are over-collected and the strength is reduced ,especially in the forearm muscles or upper limb muscles in the absence of load .The sEMG signals can reflect the function of the muscles of patients with PD .