帕金森病患者前臂肌群负重前后表面肌电特征

摘要

目的：探讨负重前后帕金森病患者前臂表面肌电(sEMG)的变化特征。方法26例帕金森病患者和28例正常对照参加本研究。于坐位上肢屈肘无负重或负重1.5 kg静态负荷下采用表面电极引导，记录sEMG信号，并进行线性时、频分析。结果无负重时，帕金森病患者屈腕屈肌的中位频率(MF)和平均功率频率(MPF)均大于正常对照(P<0.05)，两组平均肌电值(AEMG)相比无显著性差异(P>0.05)；负重1.5 kg时，帕金森病患者AEMG显著小于正常对照(P<0.001)，两组MF和MPF相比无显著性差异(P>0.05)。帕金森病患者无负重时MF和MPF均显著大于负重时(P<0.001)，AEMG显著小于负重时(P<0.001)；而正常对照MF和MPF在负重前后均无显著性差异(P>0.05)，只有无负重时AEMG显著小于负重时(P<0.001)。结论帕金森病患者静止性震颤在sEMG上主要表现为频域参数的变化，而肢体乏力主要表现为时域参数的变化。%Objective To explore the characteristics of surface electromyogram (sEMG) of the forearm muscles of Parkinson's disease patients with or without load. Methods 26 Parkinson's disease patients and 28 healthy individuals participated in this study. All the subjects performed isometric contraction for elbow flexion without load or with a load of 1.5 kg. The sEMG signals were collected by surface elec-trodes and processed by linear time and frequency domain method. Results The values of median frequency (MF) and mean power frequen-cy (MPF) were higher in the patients than in the healthy controls without load (P<0.05). The value of average EMG (AEMG) was lower in the patients than in the healthy controls with a load of 1.5 kg (P<0.001). For the patients, the values of MF and MPF were higher without load than with a load of 1.5 kg (P<0.001), and the value of AEMG was lower without load than with a load of 1.5 kg (P<0.001). For the healthy controls, only the value of AEMG was lower without load than with a load of 1.5 kg (P<0.001). Conclusion The values of MF and MPF are higher in Parkinson's disease patients than in the healthy controls without load while the value of AEMG is lower in Parkinson's dis-ease patients than in the healthy controls with load.