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胶质瘤放疗中国专家共识(2017)

摘要

Gliomas is a global cell-originated tumor that is the most common primary intracranial tumor.World Health Organization (WHO) classification of glioma is WHO Ⅰ-Ⅳ,and WHO Ⅰ-Ⅱ are the lower-grade gliomas(LGG),WHO Ⅲ-Ⅳ are the higher-grade gliomas(HGG).With the development of modern radiotherapy and radiobiology,radiation therapy become an integral role in treating gliomas.Different grade of the gliomas will have different characteristics and treatment strategy.China expert diagnosis and treatment guildline of central nervous system glioma has been published in 2016.However,there was no relevant consensus specialized on glioma radiotherapy in China untill now.Therefore,after discussion and communication according to evidencebased medicine,a consensus was made among China Society for Radiation Oncology (CSTRO) composed of Chinese glioma experts.The consensus includes radiation therapy for HGG,LGG,diffuse intrinsic pontine glioma,ependymom,recurrent spinal cord glioblastoma,elderly patients,pediatric gliomas and pseudoprogression.The consensus will provide in-depth analysis and summarize the concernedquestion of radiation therapy in clinical work.Meanwhile,this consensus would strive to further standardize the application of radiation therapy in glioma treatment to provide evidence-based guidance.%胶质瘤是指起源于神经胶质细胞的肿瘤,是最常见的原发性颅内肿瘤,WHO中枢神经系统肿瘤分类将胶质瘤分为WHO Ⅰ-Ⅳ级,WHO Ⅰ、Ⅱ级为低级别胶质瘤,Ⅲ、Ⅳ级为高级别胶质瘤.随着现代放疗技术的发展和放射生物学的深入研究,放射治疗已成为胶质瘤的重要治疗手段之一,不同级别胶质瘤的特点不同,放射治疗原则也不尽相同.2016年,我国发布了《中国中枢神经系统胶质瘤诊断与治疗指南》,阐述了胶质瘤的诊断和综合治疗策略,但目前国内尚无针对胶质瘤放疗的相关共识.因此,中华医学会放射肿瘤学分会胶质瘤共识撰写小组对胶质瘤放射治疗中的相关问题达成共识.该共识主要包括WHOⅢ、Ⅳ级胶质瘤、WHOⅡ级胶质瘤、弥漫性中线胶质瘤、室管膜瘤、恶性胶质瘤假性进展、胶质瘤脑脊液播散、老年和儿童胶质瘤患者等放疗相关问题.它将围绕临床工作中的焦点问题作出深入分析和归纳总结,力求进一步规范放射治疗技术在胶质瘤治疗中的应用,为大家的临床工作提供循证医学证据和实践指导.

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