电针智三针对血管性痴呆患者认知功能和行为能力的影响

摘要

目的：探讨电针智三针对血管性痴呆的疗效，为临床应用提供依据。方法采用随机数字表法将56例血管性痴呆（VD）患者随机分为电针组（电针治疗4周）和药物组（尼莫通，30 mg ，3次／d ，治疗4周），治疗前后进行简易智能状态检查量表（MMSE）、长谷川痴呆修改量表（HDS）、日常生活能力（ADL）和 P300等监测，观察2组治疗前后的变化。结果MMSE、HDS、ADL评分和P300监测均显示2组治疗后比治疗前明显改善，差异有统计学意义（P＜0.05）；电针组的疗效优于药物治疗组（P＜0.01）。结论电针智三针可改善VD患者的认知功能和生活行为能力，疗效优于尼莫通。%Objective To investigate the effect of electroacupuncture at Zhisanzhen on treating vascular dementia(VD) , and to provide evidence for clinical application .Methods 56 cases meeting the diagnostic criteria of VD were randomly alloca‐ted to electroacupuncture group (n= 28) and medication group (n= 28) .The electroacupuncture group was treated with Zhisanzhen and medication group received nimodipine(30mg ,oral ,three times a day) for four weeks .Mini‐mental state scale (MMSE) ,HDS ,ability of daily life‐rating scale(ADI‐R)and P300 were detected before and after treatment .Results Scores of MMSE ,HDS ,ADL and P300 indicated that there was significant improvement after 4‐week treatment (P<0 .05) in both two groups ;and total effective rate in electroacupuncture group was higher than that in medication group (P<0 .01) .Conclusion Electroacupuncture at Zhisanzhen could improve cognitive function and abiliiy of life activity in patients with vascular dementia , and have a better effect than that of oral nimodipine .