青年隐源性卒中和卵圆孔未闭的相关性研究

摘要

目的 探讨卵圆孔未闭(PFO)与青年隐源性卒中(CS)的相关性.方法 择取60例青年CS患者为研究组,选取同期60例非CS患者为对照组.2组均给予常规实验室检查、颅脑多普勒超声检查(TCD)、头颅MRI检查,并进行TCD发泡试验(c-TCD),比较2组生化检验、TCD发泡试验、TCD检查结果 .结果研究组PFO发生率(53.33%)显著高于对照组(10%),差异有统计学意义(P<0.05).组间饮酒吸烟史、糖尿病、高血压、冠心病发生率以及血脂指标比较差异无统计学意义(P>0.05).结论 CS患者多发生PFO,临床可针对此危险因素进一步诊断,必要时可组织会诊,采用介入治疗.%Objective To explore the correlation between young cryptogenic stroke (CS) and patent foramen ovale (PFO) . Methods From January 2012 to January 2014 ,60 young patients with cryptogenic stroke in our hospital were selected as the study group and 60 cases of non-youth CS patients were selected as the control group .Two groups were treated with routine laboratory tests ,brain Doppler ultrasound (TCD) ,MRI examination and TCD foaming test (c-TCD) .The result of biochemical tests foam ex-periments and TCD were compared between the two groups .Results In the PFO ,the study group had a significantly higher PFO (53.33% ) than that of the control group (10% ) .The two groups showed similar rate of alcohol intake history ,diabetes ,hyperten-sion ,coronary disease and blood lipid index (P> 0.05) .Conclusion CS is frequently occurred in patients with PFO ,doctors should consider it in the clinical diagnosis and ask for consultation if the interventional therapy is needed .