This paper aims to give some references for adverse drug reaction(ADR) signal detection in China, by summarizing the common used signal detection methods and rationale, such as the Reporting Odd Ratio, Proportional Reporting Ratio, Information Component and Gamma-Poisson Shrinker.%系统介绍了报告比值比、比例报告比、信息成分法、(多项)伽玛泊松分布缩减法4种常用药品不良反应信号检测方法及其工作原理,为在我国开展信号检测工作提供了参考.
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