本文利用大量的临床资料分析了不同年龄组之间,同一年龄组不同患儿之间,同一机体不同部位,以及同一感染的不同阶段对感染的免疫反应的不同表现,从病理和免疫发生等方面提出了新的假说,对临康治疗有一定指导意义.%Based on a 30-year clinical observation on the local pathological changes in the subcutaneous infection among children of different ages, the author raised a hypothesis as the following: 1.. The development of the local immunity to staphylococci is in stages similar to that of ana-phylaxis and desensitization reaction to T.A.T. (tetanus anti-toxin) injection.Different stage likes to appear in different age group. The new-borns may have a very low antigen-antibody reaction, give rise a nypoergic local pathology, like that of the neonatae phlegmon of the back of a newborn .Infants react too extensively to staphylococci, presenting as a wide spreading induration of the neck, anaphylactic or hyperergic reaction, like in the infantile sub-maxillary cellulitis. As the children grown up, they will react normally to a usual-dosage sta-phylococcal contamination forming a localized abscess or showing mild or even no clinical inflammation i.e., desensitization and effective immunity formation.2. The natural course of the development of local, immunity includes: no immunity reaction, hypersensitivity, stable and effective immunity, and gradual fading off of the immunity unless subsequent provocation. 3. Among children of the same age group, different local pathology under different special immunological condition could be observed.
展开▼
