部分脾栓塞治疗小儿脾机能亢进

摘要

Six patients with beta-thalassemia major and four patients with hereditary spherocytosis underwent partial splenic embolization (PSE)as alternative to splenectomy for hypersplenism,age ranged 1-5 yrs.About 50% -60%of the spleen being embolized with Gelfoam(0.5mm×0.5mm×1.0mm).all patients were followed up from 6 to 12 mos.These results disclosed elevation of white blood cell count(P＜0.01),the platelet count(P＜0.01),significant shrinking of spleen(P＜0.01＝.but normal lymphocyte subsets and immunoglobulin.Ten patients had low fever and mild oain in left hypochondrium,there was no splcnic abscess nor other noticible complications during the treatment.%总结了应用部分脾栓塞术治疗10例小儿血液病脾肿大、脾机能亢进的近期临床疗效,全部病例随访6个月以上.术后血小板及白细胞计数均较术前有显著升高,术后输血量明显减少,脾脏较术前显著缩小,脾机能亢进得到很好地控制,而机体免疫球蛋白各值,T淋巴细胞亚群及天然杀伤细胞百分值均较治疗前无显著变化.