脑瘫痉挛性马蹄足腓肠肌组织化学和超微结构观察

摘要

Twenty-four biopsy specimens of the gastrochemius muscles were taken from 12 surgical treated cases with spastic equina deformity. There were examined histochemically by myosin ATP ase method and studied ultra-structurally. The histochemical change is that the type I fibers, slow-twitch fibers, occupy a significantly higher proportion than control, and offten gather together to form type grouping. Ultra-structural abnormalities were found in all of the 24 specimens. The results showed that the surgical treatment of spastic equina deformity was usually ineffective in long term, because there was not only disorder of the central nervous system but also the change of the muscle fiber types.%对24个脑瘫痉挛性马蹄足经手术治疗后的腓肠肌标本进行肌球蛋白ATP酶组化研究和超微结构观察.组织化学的主要改变是Ⅰ型肌纤维(慢缩纤维)比例增多和Ⅰ型肌纤维的聚集,全部标本均可见到超微结构异常.结果表明,脑瘫痉挛性马蹄足外科手术治疗远期效果不佳,除中枢神经系统失调外,还与腓肠肌肌纤维型转变有关.