目的：明确肌力与身体成分、25（ OH） D3、骨密度之间的具体关系，探讨肌力训练联合骨质疏松基础治疗与单纯基础治疗在疗效上的差异。方法选择老年骨质疏松症患者120例，分为A、B两组，A组患者予阿法骨化醇片治疗，B组患者在A组治疗的基础上联合肌力训练，利用肌力检测装置，双能X线骨密度仪，ELISA试剂盒等检测A、B两组治疗前后仰卧推举，负重蹲起，负重屈肘，握力的最大肌力，脂肪含量、瘦体重等身体成分，血清25（OH）D3水平及L1－L4、左侧股骨颈的骨密度值。结果 A、B两组患者肌力与脂肪含量、体脂百分比呈负相关（－1＜r＜0，P＜0．001），与瘦体重、血清25（OH）D3水平、骨密度呈正相关（0＜r＜1，P＜0．001）；A、B两组治疗后较治疗前血清25（OH）D3水平、骨密度的增高具有统计学意义（P＜0．001），且B组疗效优于A组，具有统计学意义（P＜0．05）。结论肌力与脂肪含量、体脂百分比呈负相关，与瘦体重、血清25（OH） D3水平、骨密度呈正相关；阿法骨化醇片能够提高血清25（ OH） D3水平、骨密度，肌力训练与之结合起到协同作用，身体成分在治疗前后则变化不大。%Objective To investigate the correlation between muscle strength and body composition, 25(OH)D3, and BMD, and to explore the different efficacy between strength training associated with basic treatment of osteoporosis and basic treatment of osteoporosis alone.Methods A total of 120 senile patients with osteoporosis were selected.The patients were divided into two groups:Group A and Group B.Patients in Group A were treated with alfacalcidol tablets, while patients with Group B were treated with the strength training associated with alfacalcidol tablets.Before and after treatment, the maximum muscular strength of bench press, weight bearing squat, weight bearing elbow flexion, and grip were measured using a muscular strength detection device.The fat content, lean body mass, and the serum level of 25(OH)D3 were also detected.The bone mineral density (BMD) of L1-L4 and the left femoral neck was detected using dual-energy X-ray absorptiometry.Results The muscle strength in both groups was negatively correlated with fat content and the percentage of body fat (-1展开▼
