2639例眼睑肿物临床病理分析

摘要

Objective To describe the histopathologic spectrum and patient characteristics of eyelid tumors in Beijing Tongren Hospital.Methods It was a claims database analysis.A total of 2639 evelid tumors verified histopathologically from January 1997 to December 2006 were included in the study.Results of the 2639 eyelid tumors,the 5 most common eyelid benign lesions were inflammatory lesion.melanocytic nevus,papilloma,dermoid cyst and epidermoid cyst,and epithelial cyst.The 5 leading eyelid malignant tumors were basal cell carcinoma,sebaceous gland carcinoma,lymphoma,squamous cell carcinoma and melanoma.The mean age at diagnosis was 61 years for basal cell carcinoma and sebaceous gland carcinoma.57 years and 52 years for squamous cell carcinoma and melanoma,respectively,and 48 years for lymphoma.There was no significant sex predilection in basal cell carcinoma and sebaceous dand carcinoma.Melanoma and lymphoma occurred more commonly in women,whereas squamous cell carcinoma occurred more commonly in men.Conclusions Basal cell carcinoma and sebaceous gland carcinoma were the most common malignant eyelid tumors,and lymphoma ranked third and had an increasing trend.The malignant tumors occurred predominantly in the elderly of 60 years and above.%目的 探讨眼睑肿物的疾病谱系及病理特征.方法 为存档资料分析.收集1997年1月至2006年12月10年间存档的2639例眼睑肿物临床组织病理学资料进行分析.结果 位于良性病变前5位的分别是炎性病变、色素痣、乳头状瘤、皮样囊肿及表皮样囊肿、上皮囊肿;位于恶性肿瘤前5位的分别是基底细胞癌、皮脂腺腺癌、淋巴瘤、鳞状细胞癌、黑色素瘤.此5种恶性肿瘤患者的平均年龄分别为61、61、48、57及52岁.基底细胞癌和皮脂腺腺癌患者性别倾向不明显,黑色素瘤和淋巴瘤女性患者较多,鳞状细胞癌男性患者较多.结论 基底细胞癌和皮脂腺腺癌仍是最常见的眼睑恶性肿瘤,淋巴瘤位于第三位且有增加的趋势.眼睑恶性肿瘤主要发生于60岁以上的老年人.